Study looks at efficacy of hemoglobin thresholds for transfusion

For patients with acute myocardial infarction (MI) and anemia, 30-day risks for death or recurrent MI seem to increase with lower hemoglobin thresholds for transfusion, according to research published online Oct. 1 in the Annals of Internal Medicine.

Gerard T. Portela, Ph.D., from the University of Pittsburgh, and colleagues estimated the efficacy of four individual hemoglobin thresholds (anemia in a secondary analysis of the Myocardial Ischemia and Transfusion (MINT) trial conducted in 144 sites in six countries. Data were included for 3,492 MINT trial participants with acute MI.

The researchers found that the 30-day risk for death or recurrent MI (death/MI) was 14.8, 15.1, 15.9, and 18.3 percent for a

“The imprecision of these estimates, however, prevents explicit recommendations about individual hemoglobin transfusion thresholds,” the authors write.

More information:
Gerard T. Portela et al, Effect of Four Hemoglobin Transfusion Threshold Strategies in Patients With Acute Myocardial Infarction and Anemia, Annals of Internal Medicine (2024). DOI: 10.7326/M24-0571

Evan M. Bloch et al, Relaxing Transfusion Thresholds for Patients With Myocardial Infarction: Findings From the MINT Trial, Annals of Internal Medicine (2024). DOI: 10.7326/M24-0895

2024 HealthDay. All rights reserved.

Citation:
Study looks at efficacy of hemoglobin thresholds for transfusion (2024, October 1)
retrieved 6 October 2024
from https://medicalxpress.com/news/2024-10-efficacy-hemoglobin-thresholds-transfusion.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.





Source link

Leave a Reply

Your email address will not be published. Required fields are marked *

Explore More

Study finds YTHDF1 promotes cardiac fibrosis by enhancing AXL translation

Credit: Han Wu, Weitao Jiang, Ping Pang, Wei Si, Xue Kong, Xinyue Zhang, Yuting Xiong, Chunlei Wang, Feng Zhang, Jinglun Song, Yang Yang, Linghua Zeng, Kuiwu Liu, Yingqiong Jia, Zhuo

Scientists discover a hidden switch that shuts down inflammation

Researchers at University College London (UCL) have identified a biological mechanism that helps the body bring inflammation to an end, a finding that could eventually lead to new treatments for

Evening vs. morning dosing of blood pressure medication: No differences seen

Credit: Unsplash/CC0 Public Domain In two trials, one in frail elderly patients, evening administration of BP-lowering medications had no clinical benefits over morning administration, according to late-breaking research presented in