Positive airway pressure use tied to lower cardiovascular events

Home / Articles / Positive airway pressure use tied to lower cardiovascular events

Positive airway pressure use tied to lower cardiovascular events

September 21, 2024 admin 0 Comments 0 tags

Positive airway pressure (PAP) utilization is associated with lower all-cause mortality and major adverse cardiovascular event (MACE) incidence in older adults with obstructive sleep apnea (OSA), according to a study published online Sept. 11 in JAMA Network Open.

Diego R. Mazzotti, Ph.D., from the University of Kansas Medical Center in Kansas City, and colleagues sought to determine whether PAP initiation and utilization are associated with lower mortality and incidence of MACE among older U.S. adults with OSA. The analysis included 888,835 Medicare beneficiaries with two or more distinct OSA claims identified from multistate, statewide, multiyear Medicare fee-for-service claims data (2011 to 2020) with follow-up until death or censoring through 2020.

The researchers found that during a median follow-up of 3.1 years, those with evidence of PAP initiation (32.6 percent) had significantly lower all-cause mortality (hazard ratio, 0.53) and MACE incidence risk (hazard ratio, 0.90). There was a progressive association between higher quartiles of annual PAP claims and lower mortality and MACE incidence risk.

“These results might inform future trials assessing the importance of obstructive sleep apnea therapies toward minimizing cardiovascular risk and mortality in older adults,” the authors write.

One author disclosed being a cofounder of Hypnoscure.

More information:
Diego R. Mazzotti et al, Positive Airway Pressure, Mortality, and Cardiovascular Risk in Older Adults With Sleep Apnea, JAMA Network Open (2024). DOI: 10.1001/jamanetworkopen.2024.32468

Citation:
Positive airway pressure use tied to lower cardiovascular events (2024, September 17)
retrieved 21 September 2024
from https://medicalxpress.com/news/2024-09-positive-airway-pressure-cardiovascular-events.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

Source link

Explore More

Children sleep problems associated with psychosis in young adults

Children who experience chronic lack of sleep from infancy may be at increased risk of developing psychosis in early adulthood, new research shows. Researchers at the University of Birmingham examined

Marianna Spring Social media investigations correspondent BBC/Getty Images Gabriel and Sebastian Shemirani watched with concern as their mother Kate rose to notoriety during the pandemic, eventually getting struck off as

For many southwestern Pennsylvania students, this school year has already included days away from the classroom because of the buildings themselves. Mold has closed schools in at least four districts,