Injecting nivolumab (Opdivo) directly into precancerous oral lesions led to a reduction in lesion size and allowed some patients to avoid surgery, according to research from a Phase I clinical trial presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17–22.
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Intralesional nivolumab may be effective against precancerous oral lesions, Phase I trial results indicate
April 21, 2026
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