Activation of parkin by the tetrahydropyrazolo-pyrazine (THPP) BIO-2007817 in the presence of pUb. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-51889-3 More than 100,000 Canadians currently live with Parkinson’s disease. A novel
Gait measurement experiment. Credit: 2024, Arai et al., Interlimb coordination is not strictly controlled during walking, Communications Biology Walking is an activity that is often taken for granted. Most people
Higher exposure to air pollution increases the risk for Parkinson’s disease (PD), according to a study published online Sept. 16 in JAMA Network Open. Brittany Krzyzanowski, Ph.D., from the Barrow
Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114540 Northwestern Medicine investigators have uncovered a new way in which neurons in the brain “forget” associations that help guide behavior and habits, according to
Credit: Pixabay/CC0 Public Domain Eating the seaweed Ecklonia cava may be able to slow down or prevent Parkinson’s disease, according to a 2024 study. Researchers found that antioxidants in the
Prolonged imbalance in glucose metabolism increases RAN translation and accumulation of DPRs, heightening neuronal vulnerability in in vitro and in vivo models of C9orf72-ALS/FTD. C9-BAC mice show dysregulated brain metabolite
A neural pathway known as the “tremor network” regulates movement and runs between the motor cortex (A), thalamus (B) and cerebellum (C). Messages need to flow smoothly along this network,
In 1817, a British physician named James Parkinson published An Essay on the Shaking Palsy, describing for the first time cases of a neurodegenerative disorder now known as Parkinson’s disease.
Survival curves for time to Parkinson disease diagnosis. Credit: JAMA Network Open (2024). DOI: 10.1001/jamanetworkopen.2024.31949 A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) found the risk
A pipeline to explore candidate target genes using transcriptomics and unknomics. Credit: Takayuki Suzuki/Hiroshima University A research team from Hiroshima University has developed an analysis pipeline to identify unexploited genes
