Category: ENDOCRINOLOGY

Boys with higher levels of environmental pollutants enter puberty later, study finds

Credit: Unsplash/CC0 Public Domain New findings, published in the journal Environmental Science & Technology, analyze a group of pollutants called per- and polyfluoroalkyl substances (PFAS), which consist of chemicals used

Urate transporter structures reveal the mechanism behind important drug target for gout

Cryo-EM structures of human URAT1 in different functional states. Credit: Cell Research (2024). DOI: 10.1038/s41422-024-01023-1 Scientists at St. Jude Children’s Research Hospital have used cryo-electron microscopy to generate ten structures

Long-term exercisers have ‘healthier’ belly fat, study reveals

Comparison of aSAT remodeling capacity between EXev versus SEDev. Credit: Nature Metabolism (2024). DOI: 10.1038/s42255-024-01103-x People with obesity who are long-time exercisers have healthier belly fat tissue and can store

Common diabetes drug slows growth of normal cells carrying cancer mutation, finds study

PIK3CA mutant clones in human esophageal epithelium. Credit: Nature Genetics (2024). DOI: 10.1038/s41588-024-01891-8 A common diabetes medication, metformin, slows the growth of precancerous cells in the esophagus while some metabolic

Swallowing triggers a release of serotonin, research reveals

Larvae of the fruit fly Drosophila have a kind of stretch sensor in the esophagus (grey structure in the middle) that reports swallowing processes to the brain. If food is

Study reveals how insulin-producing cells work together to respond to metabolic demands

Modulation of individual IPCs by aminergic and peptidergic neurons in patch-clamp recordings. Credit: eLife (2024). DOI: 10.7554/eLife.99548.1 Scientists have revealed how a population of insulin-producing cells (IPCs) in the fruit

Danish study finds only children enter puberty significantly earlier than children with siblings

Credit: Pixabay/CC0 Public Domain A new Danish study shows that children without siblings or with half- or step-siblings enter puberty significantly earlier than children with biological siblings. The study provides

Finding the right pathway to reduce fat accumulation in the liver

Graphical Abstract. Credit: International Journal of Molecular Sciences (2024). DOI: 10.3390/ijms25137277 Using a novel stem cell platform, a team of MUSC researchers has identified a pathway that could be targeted

Genes with strong impact on menopause timing also link to cancer risk

Credit: Unsplash/CC0 Public Domain New research has found four genes with some of the largest known effects on the timing of menopause discovered to date, providing new insight into links

Lifestyle intervention from childhood to adolescence affects metabolism even years later, finds study

Credit: iScience (2024). DOI: 10.1016/j.isci.2024.110295 A new study from the University of Eastern Finland (UEF) uncovers how early lifestyle changes can have long-lasting impacts. A diet and physical activity intervention