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Esketamine shows promise for treatment-resistant depression

Total scores in TRANSFORM-1 and TRANSFORM-2. Credit: CNS Spectrums (2024). DOI: 10.1017/S1092852924000105 An estimated one-third of patients with major depressive disorder have treatment-resistant depression (TRD), characterized by an inadequate response

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French psychiatrists of the 19th century may be unsung heroes of modern melancholia research

Credit: Alex Green from Pexels In an era where mental health awareness is at the forefront of public discourse, a new historical review is shedding light on the often-overlooked French