A microphysiological system to assess drug transport and nephrotoxicity

A KyotoU team has developed a human iPS cell-derived kidney organoid-based proximal tubule-on-chip—OPTECs-on-Chip—that mimics in vivo renal physiology more closely than ever before. Credit: KyotoU/Yokokawa Lab Developing advanced drug screening

Steroid drugs used for HRT can combat E. coli and MRSA

The emergence of drug-resistant bacteria is a global threat to human health, and the development of new antibiotics from scratch is an extremely expensive and time-consuming process. To address this

Discovery illuminates how thyroid hormone ‘dims’ metabolism

It has been known for some time that the thyroid gland is a strong regulator of the body’s metabolism, making it key to many health conditions. But the molecular details