FLIpping the Switch: Boosting stem cell numbers for therapies

June 17, 2025 0 Comments 0 tags

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by

Genes combined with immune response to Epstein-Barr virus increase MS risk

June 17, 2025 0 Comments 0 tags

In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral

Engineering antibodies with a novel fusion protein

June 17, 2025 0 Comments 0 tags

The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other antibodies are used by physicians to diagnose conditions or by scientists

New genetic test can diagnose brain tumors in as little as two hours

June 17, 2025 0 Comments 0 tags

Scientists and medics have developed an ultra-rapid method of genetically diagnosing brain tumours that will cut the time it takes to classify them from 6-8 weeks, to as little as

Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer

March 16, 2025 0 Comments 0 tags

Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than

Toward improved early detection of pancreatic cancer

February 18, 2025 0 Comments 0 tags

Pancreatic cancer (PC) is the worst prognosis cancer globally, with just 13% of patients who are diagnosed with PC surviving for 5 years or more after initial diagnosis. In Ireland,

Scientists want to throw a wrench in the gears of cancer’s growth

February 5, 2025 0 Comments 0 tags

Preventing the cell’s protein factories from making the notorious cancer-causing protein MYC could stop out-of-control tumors. For decades, scientists have tried to stop cancer by disabling the mutated proteins that

Researchers create a new organoid with all key pancreas cells

December 12, 2024 0 Comments 0 tags

Researchers from the Organoid group (previously Clevers group) at the Hubrecht Institute have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early

Researchers uncover new role of mutant proteins in some of the deadliest cancers

November 12, 2024 0 Comments 0 tags

Researchers at the National Institutes of Health (NIH) and their collaborators have discovered a new way in which RAS genes, which are commonly mutated in cancer, may drive tumor growth