Scientists map how deadly bacteria evolved to become epidemic

October 8, 2024 0 Comments 0 tags

Pseudomonas aeruginosa — an environmental bacteria that can cause devastating multidrug-resistant infections, particularly in people with underlying lung conditions — evolved rapidly and then spread globally over the last 200

Cystic fibrosis: School-aged children benefit from triple combination therapy

October 8, 2024 0 Comments 0 tags

Cystic fibrosis is a hereditary disease that so far has been incurable. Those affected have thick, viscous mucus secretions in their lungs, and lung function diminishes steadily over time. Today,

Prime editing efficiently corrects cystic fibrosis mutation in human lung cells

October 8, 2024 0 Comments 0 tags

Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection. A three-drug cocktail

How an emerging disease in dogs is shedding light on cystic fibrosis

October 8, 2024 0 Comments 0 tags

A canine gallbladder disease that involves the accumulation of abnormal mucus similar to that seen in human cystic fibrosis (CF) patients is caused by improper expression of the gene associated

Prescribed opioids raise risk of pneumonia in patients with and without HIV

October 8, 2024 0 Comments 0 tags

Taking prescribed opioids raises the risk of pneumonia in individuals with and without HIV, a new Yale-led study finds. The study, published in JAMA Internal Medicine, reinforces the concern that

Reevaluating pneumococcal vaccine guidance: An analysis

October 8, 2024 0 Comments 0 tags

If mitigating racial disparities in those who contract pneumococcal diseases, such as meningitis and pneumonia, is a top public health priority, then recommending that all adults get a pneumococcal vaccine

Winning the arms race: Analysis reveals key gene for bacterial infection

October 8, 2024 0 Comments 0 tags

To successfully infect their hosts, bacteria need to evade the host immune system in order to reproduce and spread. Over the course of evolution, hosts — such as humans —

PCV10 pneumococcal vaccine has big impact in Kenya, even among unvaccinated individuals

October 8, 2024 0 Comments 0 tags

A vaccine against Streptococcus pneumoniae, a major cause of childhood illness and mortality in the developing world, sharply reduced the incidence of serious pneumococcal disease among children in a large

Many kids with pneumonia get unnecessary antibiotics, chest X-rays

October 8, 2024 0 Comments 0 tags

Preschool children with community-acquired pneumonia often receive unnecessary tests and treatment at outpatient clinics and emergency departments, according to a nationally representative study led by Todd Florin, MD, MSCE, from

Pneumonia mapped in largest genomic survey of any disease-causing bacterium

October 8, 2024 0 Comments 0 tags

Researchers have mapped the most common bacterial cause of pneumonia around the world and revealed how these bacteria evolve in response to vaccination. Scientists from the Wellcome Sanger Institute, Emory