Category: NEUROLOGY

Genetic variants linked to Alzheimer’s trigger brain inflammation in females, preclinical study finds

Inflammatory microglia from a female brain in a mouse model of Alzheimer’s disease. The mice also carry the APOE4 and TREM2 genetic risk factors. Yellow dots indicate that these microglia exhibit a senescent phenotype. Credit:

Risk of developing depression and anxiety is higher in those with cerebral palsy

Adults with cerebral palsy have a higher risk of developing depression and anxiety than their peers without the condition, a new study in the journal JAMA Neurology reports. A team

Dementia diagnostic markers shown to change with time of day

Levels of plasma p-tau217 (LS-means ± SE) across a 24-h period in PLWA, their study partners, and cognitively intact older adults. Credit: Translational Psychiatry (2024). DOI: 10.1038/s41398-024-03084-7 The time of day when

Community-based programs in senior centers may lower health care use and costs for people with dementia

Predicted outcomes in 2019 for residents in smaller jurisdiction (sj) areas. Credit: Health Affairs Scholar (2024). DOI: 10.1093/haschl/qxae108 Living with dementia in communities with senior centers providing access to adult

Chronic pain linked to increased risk of dementia in older Australians

Changes in the prevalence of dementia by age and gender from 2015 to 2018. Credit: Value in Health (2024). DOI: 10.1016/j.jval.2024.07.022 Older Australians suffering from chronic pain face a significantly increased

Promising Alzheimer’s drug candidate prevents buildup of tau proteins in lab and fruit fly studies

The brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to

Key mechanisms in asymptomatic Alzheimer’s disease brains offer potential protection against cognitive decline

Microglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit: Acta Neuropathologica (2024). DOI: 10.1007/s00401-024-02775-1 Researchers at Indiana University School of Medicine are

Stroke associated with accelerated long-term cognitive decline

Credit: Pixabay/CC0 Public Domain New evidence from the Centre for Healthy Brain Ageing (CHeBA) indicates that older adults who experience a stroke for the first time will have substantial immediate

Study reveals regional differences in dementia drug use in nursing homes

Credit: Pietro Jeng from Pexels Variations in the use of antidementia and antipsychotic drugs for nursing home residents with dementia across the United States suggest a need for better guidance

Smartphone-assisted wayfinding task identifies people at risk for dementia

Credit: Pixabay/CC0 Public Domain Researchers from DZNE and Otto von Guericke University Magdeburg have identified individuals with increased risk for dementia using mobility data, recorded during a smartphone-based wayfinding task