Study reveals sex-specific gene expression in adipose stem cells of mice

September 21, 2024 0 Comments 0 tags

Outline and cell type characterization. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-51867-9 Researchers at Karolinska Institutet and AstraZeneca have discovered that gene expression in adipose stem cells varies according to sex

Weight loss drugs could help fight fatty liver disease

September 21, 2024 0 Comments 0 tags

Graphical abstract. Credit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.07.023 In the fight against fatty liver disease, researchers are looking for any and all possible solutions. But to combat the disease, which

A microphysiological system to assess drug transport and nephrotoxicity

September 21, 2024 0 Comments 0 tags

A KyotoU team has developed a human iPS cell-derived kidney organoid-based proximal tubule-on-chip—OPTECs-on-Chip—that mimics in vivo renal physiology more closely than ever before. Credit: KyotoU/Yokokawa Lab Developing advanced drug screening

New research finds higher levels of leptin indicate brain protection against late-life dementia

September 21, 2024 0 Comments 0 tags

Credit: CC0 Public Domain New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting

Study links hot flashes to brown adipose tissue activity, childhood exposure to cold

September 21, 2024 0 Comments 0 tags

Credit: Pavel Danilyuk from Pexels New research from the University of Massachusetts Amherst reveals links between menopausal hot flashes, cold experienced during childhood, and increased activity in brown adipose tissue

Sex hormones modulate the immune system to influence disease risk differently, research reveals

September 14, 2024 0 Comments 0 tags

Credit: Pixabay/CC0 Public Domain Scientists from the Karolinska Institutet in Sweden and Imperial College London have shown for the first time which aspects of our immune systems are regulated by

Study solves testosterone’s paradoxical effects in prostate cancer

September 13, 2024 0 Comments 0 tags

Low dose androgens do not facilitate receptor dimerization. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52032-y A treatment paradox has recently come to light in prostate cancer: Blocking testosterone production halts tumor

Boys with higher levels of environmental pollutants enter puberty later, study finds

September 13, 2024 0 Comments 0 tags

Credit: Unsplash/CC0 Public Domain New findings, published in the journal Environmental Science & Technology, analyze a group of pollutants called per- and polyfluoroalkyl substances (PFAS), which consist of chemicals used

Urate transporter structures reveal the mechanism behind important drug target for gout

September 13, 2024 0 Comments 0 tags

Cryo-EM structures of human URAT1 in different functional states. Credit: Cell Research (2024). DOI: 10.1038/s41422-024-01023-1 Scientists at St. Jude Children’s Research Hospital have used cryo-electron microscopy to generate ten structures

Long-term exercisers have ‘healthier’ belly fat, study reveals

September 13, 2024 0 Comments 0 tags

Comparison of aSAT remodeling capacity between EXev versus SEDev. Credit: Nature Metabolism (2024). DOI: 10.1038/s42255-024-01103-x People with obesity who are long-time exercisers have healthier belly fat tissue and can store