A KyotoU team has developed a human iPS cell-derived kidney organoid-based proximal tubule-on-chip—OPTECs-on-Chip—that mimics in vivo renal physiology more closely than ever before. Credit: KyotoU/Yokokawa Lab Developing advanced drug screening
Credit: CC0 Public Domain New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting
Credit: Pavel Danilyuk from Pexels New research from the University of Massachusetts Amherst reveals links between menopausal hot flashes, cold experienced during childhood, and increased activity in brown adipose tissue
Credit: Pixabay/CC0 Public Domain Scientists from the Karolinska Institutet in Sweden and Imperial College London have shown for the first time which aspects of our immune systems are regulated by
Low dose androgens do not facilitate receptor dimerization. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52032-y A treatment paradox has recently come to light in prostate cancer: Blocking testosterone production halts tumor
Credit: Unsplash/CC0 Public Domain New findings, published in the journal Environmental Science & Technology, analyze a group of pollutants called per- and polyfluoroalkyl substances (PFAS), which consist of chemicals used
Cryo-EM structures of human URAT1 in different functional states. Credit: Cell Research (2024). DOI: 10.1038/s41422-024-01023-1 Scientists at St. Jude Children’s Research Hospital have used cryo-electron microscopy to generate ten structures
Comparison of aSAT remodeling capacity between EXev versus SEDev. Credit: Nature Metabolism (2024). DOI: 10.1038/s42255-024-01103-x People with obesity who are long-time exercisers have healthier belly fat tissue and can store
PIK3CA mutant clones in human esophageal epithelium. Credit: Nature Genetics (2024). DOI: 10.1038/s41588-024-01891-8 A common diabetes medication, metformin, slows the growth of precancerous cells in the esophagus while some metabolic
Larvae of the fruit fly Drosophila have a kind of stretch sensor in the esophagus (grey structure in the middle) that reports swallowing processes to the brain. If food is
